In this draft policy briefing on partnership we explain the GRNPP experience of managing international research coalitions. Richard Axelby, Emma Crewe, Sewit Hailesalassie, Jas Kaur, Myat Thet Thitsar and Bethel Worku-Dix outline how we have been managing and learning about grant-making, partnership and evaluation since 2017. We also offer principles and practical recommendations about how to engage in ethical grant-making and partnership. Evidence that our approach works can be found on our partners’ research pages and in this output library. This policy briefing is still in draft and the final version is currently designed by Research Retold.